Bovine milk is an excellent source of bioactive peptides. The bioactive peptides are in an inactive state in the protein and are released during enzymatic activity, e.g. during cheese ripening. Specific properties of bioactive peptides from ripened cheese has been reported, e.g. antihypertensive, antioxidative, antimicrobial, immunomodulatory and mineral binding.

Measurement of plasma concentrations of natriuretic peptides have been suggested to be of diagnostic and prognostic value in canine cardiac disease. In several previous canine studies, however, a considerable overlap between investigated groups has been identified. A reliable natriuretic peptide test for use in clinical practice requires establishment of reference values for natriuretic peptides in healthy dogs and cut-off values for subclinical disease as well as for clinical signs of congestive heart failure. Numerous physiological, pathological and pharmacological factors, aside heart function, may influence concentration of natriuretic peptides. A potential effect of dog breed on natriuretic peptide concentration has been suggested but has, to our knowledge, not previously been specifically studied.

Abstract Tripeptidyl-peptidase II (TPPII), is present in most eukaryotic cells. It cuts tripeptides from the N-terminus of peptides and is especially important for degrading peptides longer than 15 amino acids. TPPII also tailors long peptides into suitable substrates for the enzymes which transport and produce the peptides that MHC I present. Increased levels of TPPII have also been found in certain cancer cells, thus it is of interest to determine if TPPII could be used as a tumour marker.The aim of this study was to optimise and evaluate 3 different methods for quantifying TPPII. Western blot, enzyme-linked immunosorbent assay (ELISA) and fluorophore-linked immunosorbent assay (FLISA) protocols were optimised regarding incubation times and antibody dilutions.

Fibroblast growth factors are signaling peptides that controls important cellular processes such as proliferation, differentiation, migration, adhesion and survival. Through binding to different types of receptors on the cell surface, these peptides can have different effect on the target cell. Which effect that is achieved depends on many factors. Thus, each of the 24 known FGFs different biological responses. The FGF receptors (FGFR 1-4) initiates different intracellular pathways which in turn leads to different biological responses.

The aim of this project was to improve taste of a liquid food product, comprising extremelybitter and unpalatable amino acids and one unrevealed ingredient. The amino acids were Lleucine,L-isoleucine, L-valine, L-threonine and L-lysine monohydrochloride. Experimentaldesign was set up as a screening of water solutions comprising these ingredients (called BCAAsolutions) and added ingredients with potential to improve flavour. BCAA solution withingredients that were potential bitterness suppressors were evaluated in flavour, bitternessand/or palatability. Solutions of separate amino acids were also studied.

This bachelor thesis in science Informatics contains the qualifications for the applying of IT in education for students in elementary school, grade 1-3. By empirical case study on an existing elementary school, whose success on IT use is noticed, describes how to apply IT in the classroom in an adequate way. We look at different theoretical frameworks in interaction and design of systems designed for learning purposes, and satisfies their specific needs and situations within the classroom's four walls. The current lack of statistical measurements on students' results and effects of the use of IT in teaching, prevents further improvements. If we simultaneously work to develop more well-designed systems that are designed for this purpose, it is possible that the effects become more and better.

SMTP, the current protocol for sending electronic mail (e-mail) over the Internet, has for many years suffered from several problems and limitations. When it was designed, well over twenty years ago, the requirements for e-mail were very different from those of today. A message was a text message in English, and both user and machine were explicitly named in the address. The protocol was not designed to transfer other types of messages, and no mechanism was included to verify the identity of the sender.In order to solve these shortcomings, a new e-mail protocol needs to be defined. This report specifies a basis for what such a protocol may look like.

ABB Surge Arrestors in Ludvika have for a long time had a problem to keep the moisture at a steady state in the production of their ZnO-powder, that is used to produce varistors.Some black-box models of the spray drying process have been designed and evaluated to find a solution for the problem. After evaluating the collected data it has been found that variations in the supply voltage causes control difficulties for the operator. A cascade control system was designed, consisting of three PI control loops designed with lambda tuning. The disturbance in the supply voltagewas used as a feed forward in the control system.At the end of the project the control system was installed, and tests were made to verify the functionality of the regulator. It was shown that most of the variations in the moisture of the powder could be eliminated using small resources, through purchase of a process controller and four power meters.

The reindeer planning system (Renbruksplanen, RBP) is a communication and planning tool designed for Sami groups. A key purpose of this is that it will act as a tool in consultation with other market players, including forestry. Sami groups have asked for a model of how this can be used in a flexible manner. With the Swedish Forest Agency as a project manager, a communication model for how to use the RBP has been designed. It consists of a number of points divided into ?before?, ?during? and ?after? the consultation.

This thesis examines information visualization, infographics, as a method of advertising. To answer the initial research question of what makes infographics an appropriate method for print advertising, a practical infographic-based advertising campaign has been designed. This, together with three other campaigns, has been the basis for an analysis focused on function, appeal and persuasion. The result tells us that there are benefits to using infographics for an advertising purpose, because the method can act both attention-grabbing and convincing, depending on how it is used and designed..

The purpose of this study is to examine how activities are looked upon, organized and put into practice at homes designed for the elderly. To achieve this we have done a survey study, based upon the caregiver´s point of view regarding the subject activity. The result of this study has been interpreted and analyzed with help from the engagement- and disengagement theories. The result shows us that the caregiver´s find the term activity slightly abstract, and rather difficult to define. All of the caregiver´s did agree on the matter that it?s good to activate elderly people and that the elderly people are activated at a large extent.

This study will examine if caregivers, working with people with dementia problems, is in need of support and in what way they see how the support should be designed. Previous research shows that there are many factors in elderly care that affect all of the caregivers. Working with people in this sort if dependence, requires a lot of the caregivers, both mentally and physically. To study if the caregivers consider themselves to be in need of support, and in what way they see how the support should be designed, the study employs a qualitative approach using to types of interviews, one focus group with four assistant nurses, and two individual in-depth interviews with the administrative personnel and one nurse. The results show that the need for support for the caregivers exists. Caregivers working with people with dementia problems, daily face difficulties, some more difficult to handle than others.

This thesis describes how the chip space and coolant channels are designed in today?s mills, the ideas behind the design and what is considered to be the best method of cooling. It contains ideas on how the chip space can be simplified. It contains several concepts on how the cooling could be designed for better efficiency and manufacturability. There are also suggestions on how the cooling could be stopped when the cutter isn?t cutting.

This project is an attempt at creating a bag that is both functionaland has an interesting and relevant visual appearance. I have found that a bag that is functional usually have adapted certain aesthetics which are appealing only to a very limited target group. At the same time many bags that are more focused on style can be downright disabling to the carrier. I wanted to create a functional bag, and to explore new functions doing this, while working with aesthetics that stayed relevant and interesting to my target group. The bag was designed for the company Åhléns and their label WERA Stockholm, and theircustomers was the target group.

Tripeptidyl peptidase II (TPPII) is an exopeptidase which cleaves tripeptides from theN-terminus of peptides. The exact functional role of TPPII is still a matter of investigation. Itis believed that the enzyme is primarily involved in intracellular protein degradation, where itcooperates with the proteasome and other peptidases to degrade proteins into free aminoacids. These amino acids can subsequently be used in the production of new proteins. The aimof this work was to express murine wild type TPPII using E.